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 Bacteria, viruses and parasites are in their element when they come in contact with the host cell. Studying these interactions has led to advancements in the fields of highly infectious diseases such as HIV, malaria and tuberculosis. Imaging the pathogen infecting a cell requires high-speed hardware and optimized software to generate 3D images but sensitive enough to keep the host cell alive. DeltaVision systems excel in this capability and are used to study a wide variety of microbes and host cell responses in leading institutions worldwide.
Associated Papers
- Visualization of the intracellular behavior of HIV in living cells
David McDonald, Marie A. Vodicka, Ginger Lucero, Tatyana M. Svitkina, Gary G. Borisy, Michael Emerman, and Thomas J. Hope.
J. Cell Biol., Nov 2002; V159, p 441.
- download pdf -
- A Membrane Network for Nutrient Import in Red Cells Infected with the Malaria Parasite
Sabine A. Lauer, Pradipsinh K. Rathod, Nafisa Ghori, and Kasturi Haldar.
Science, May 1997; V276, p 1122.
- download pdf -
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DeltaVision® is a family of fully integrated, optimized microscopy systems designed to look at multiple probes and samples over longer periods of time than other imaging systems. These systems are uniquely suited for 3D and 2D live cell applications. As biological questions increase in complexity and sensitivity, there is a greater need for higher image quality. Improved resolution and contrast yield greater quantitative measurements, and therefore more reliable results. |
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