ISSAQUAH, Wash. - 15 Dec, 2002 - Applied Precision, LLC announces the introduction of the DeltaVision Spectris, their newest high resolution, image restoration microscopy system. The system sports an entirely new look, with a fully integrated ergonomic workspace and space efficient design. The imaging system has undergone a significant evolution, with a newly designed light path that delivers more focused illumination of the sample, extending the linear range of fluorescent data. Additionally, a new light detection system captures more information faster, allowing for improved real-time imaging, especially important in live-cell experiments.

Recent studies published in PNAS, Traffic, and BioTechniques point to image restoration technology as being the most accurate and quantifiable in the industry for 3D deconvolution and comparison of cellular and intracellular fluorescence.

“We built on over a decade of experience with microscopy optics and light management to develop and improve our approach; and our image restoration technology takes full advantage of the more focused illumination across the specimen for better contrast and accurate intensities within the sample”, says Mark Rand, Ph.D., Product Marketing Manager for Applied Precision’s Life Sciences group.

The DeltaVision Spectris Image Restoration Microscopy System is based on wide-field epi-fluorescence microscopy imaging and “precisionware” – Applied Precision’s patented convergence of electronics, optics, mechanics and software. Applied Precision's unique engineering expertise has generated a product ideally suited for high-end quantitative biological imaging.

Hundreds of publications from cell biologists worldwide have used DeltaVision® technology for their work focused on the understanding cell structure, motility, mechanics and division. Studying these processes, including identifying proteins and enzymes involved in cellular activities, and is crucial to understanding cancer and other life-threatening diseases.

“We recognize the significance of the research being conducted with our systems, and we’re very excited to continue to improve the tools necessary for this critical work,” said Brent Navran, Applied Precision’s Life Sciences product line manager. “It is very important to us that top researchers in the world count on our products to speed research while obtaining both high quality and quantifiable data.”

About the DeltaVision Spectris System

The DeltaVision Spectris system provides real-time imaging capabilities to study dynamic processes within the cell, including, for example, protein transport within the nucleus. This real-time imaging feature, combined with the advanced point-visiting technique of the system, enables researchers to study multiple cells simultaneously. The system provides the imaging flexibility necessary for the best combination of spatial and temporal resolution matched to the cell structure and rate of activity. Fast exposures also reduce cell-damaging phototoxicity effects as well as minimizing photobleaching, both of which can limit observation time in live-cell imaging applications.

“With the remarkable image quality that the Spectris system delivers, researchers can discover more from their live-cell image studies than ever before, and have confidence that the results from their DeltaVision Spectris is as accurate a depiction of cellular reality as is possible,” explains Navran.

About Applied Precision, LLC.

Applied Precision develops measurement, analysis and process control systems for Life Sciences, (particularly live-cell microscopy and genomics), the semiconductor industry, and precision motion control components. Applied Precision’s specialized products are based on precisionware™, the company’s unique convergence of mechanics, electronics, optics and software. Applied Precision, LLC. has been enabling advancements in the world’s core technologies since its inception in 1985. Applied Precision (www.appliedprecision.com) can be reached in the United States at (425) 557-1000 or in the United Kingdom at +44 1672 518350.